Optimizing Veterinary and Animal Health

While traditional studies are helpful in demonstrating causal associations, the efficacy of nutritional/therapeutic interventions, or gene expression differences between healthy and diseased animals, they do not tease apart the functional metabolic changes that occur in the animal in response to a specific stimulus (whether an endogenous or exogenous factor). Thus, traditional research methods may not be sufficient to thoroughly understand disease mechanisms, identify specific biomarkers’ diagnostic and prognostic potential, or develop targeted innovative interventions that ultimately enhance animal health and wellbeing. In addition, the veterinary and animal health industries face increased demands for more comprehensive data to support product claims; speed to market and differentiated positioning require fast, efficient, and quantitative phenotyping.

With more than 20 years of metabolomics experience and continuous innovation, Metabolon has created the industry’s most advanced system for measuring and understanding the metabolome. Their team of expert systems biologists can informatively assist in study design and provide sample collection and handling guidelines. Following advanced liquid chromatography-mass spectrometry data generation, metabolite identification, data curation, and statistical analyses, Metabolon provides data interpretation and consultative support that can accelerate discovery, circumvent obstacles, and provide actionable data for your veterinary and animal health projects.

Short-chain fatty acids (SCFAs) are produced in the colon by the gut microbiota. They are the end products of anaerobic fermentation of dietary fibers and protein/peptides in the small intestine. Their formation is the result of a complex interaction between diet, gut microbiota, and host. SCFAs influence the physiology of the colon serving as energy sources by host cells and the intestinal microbiota as well as participating in different host signaling mechanisms.