Metabolomics and Microbiome Research

The microbiome refers to the various species of bacteria that colonize the human gut. The microbiome is remarkably diverse, even between healthy individuals. The metabolic importance of the human microbiome has led many to recognize it as another (in)human organ with profound metabolic significance. Microbial metabolites influence immune function, metabolism, cardiovascular health, cognition and behavior, nutrient acquisition from food, and even the effectiveness of therapeutics like chemotherapy. The wide range of metabolites produced by the microbes in our guts represents a wealth of potential biomarkers and therapeutic targets. Therefore, it is no longer enough to determine “who is there” but rather “what are they doing?” This eBook explores how metabolomics can advance our understanding of the microbiome and its impact on health.