Metabolon, headquartered in Research Triangle Park, NC, is a diagnostic products
and services company offering the industry’s leading biochemical profiling platform.
Our patented platform provides a global analysis of complex biological samples for
the discovery of markers and pathways associated with drug action and disease. This
differentiated approach enables the identification of biomarkers useful for the
development of a wide range of diagnostics and provides insight into complex biochemical
processes such as drug action, toxicology and bioprocess optimization.
Metabolon has developed and patented technology and methodologies that simultaneously
detect and quantify all of the small molecules present in complex biological specimens.
This is extremely important because these small molecules represent the products
of cellular metabolism, which change in response to disease and drug therapy.
One of the major advantages of this approach is the vast amount of biochemical information
that has been assembled from 100 years of biochemical research. Leveraging this
knowledge base, we can more easily discover biochemical biomarkers that can be used
to readily identify pathways and targets involved in disease and drugs. The unique
advantage of the biomarkers discovered by Metabolon is that biochemical markers
represent changes which are truly indicative of the drug action or disease mechanisms
and is generally not achieved through other approaches, such as transcriptomics
Metabolon’s technology is extremely robust and has been rigorously tested and validated
as a powerful tool for discovery of biomarkers of disease, drug efficacy, drug toxicity
and mechanism of action in clinical specimens by over 1500+ studies with pharmaceutical,
government and academic investigators.
Products and Services
Metabolon’s fee-for-service business is focused on product-based global biochemical
profiling solutions provided to pharmaceutical and biotechnology companies as well
as funded government and academic institutions engaged in product development activities.
We provide comprehensive biochemical profiling for a wide variety of applications,
including drug safety and efficacy studies, bioprocess optimization and consumer
product development. We are currently working with 14 of the top 15 pharmaceutical
companies and many biotechnology companies.
Please click here to learn more about Metabolon’s Academic,
Pharma/Biotech, or Consumer Products
Diagnostic Products Business
Built upon our core biomarker discovery engine, Metabolon is focused on developing,
validating and marketing molecular diagnostic assays for the detection and monitoring
of disease based in part upon biomarkers discovered from its collaborative and fee-for-service
studies. These novel biochemical biomarkers provide the basis for its diagnostic
To develop innovative and relevant molecular diagnostic assays, Metabolon focuses
biomarker discovery, targeted assay development and clinical validation studies
in diseases where treatment costs and costs associated with treatment failure are
high and current diagnostic methods are expensive, invasive or lack predictive power
for accurate diagnosis, prognosis or therapeutic monitoring of disease.
to learn more about Metabolon’s Diagnostic business.
For more information about Metabolon, please